Tag: enzymes are a type of
KRAS G12C-mutant non-small-cell lung cancer: biology, developmental therapeutics, and molecular testing
KRAS mutation is the most typical oncogenic driver in superior non-small cell lung most cancers (NSCLC), occurring in roughly 30% of lung adenocarcinomas. Over 80% of oncogenic KRAS mutations happen at codon 12 the place the glycine residue is substituted by completely different amino acids, resulting in genomic heterogeneity of KRAS-mutant tumors. The KRAS glycine-to-cysteine…
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Sequential Post-polymerization Modification of Aldehyde Polymers to Ketone and Oxime Polymers
A brand new sequential post-polymerization modification route has been developed for the synthesis of multifunctional polymers from a easy aldehyde polymer. Within the first modification step, a template polymer derived from the novel polymerization of 4-vinyl benzaldehyde undergoes Rh-catalyzed hydroacylation with alkenes to furnish a gaggle of ketone polymers. Within the second modification step, Schiff…
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