MIT International Polymer Trade Corporation

Polygermanes are germanium-based analogues of polyolefins and possess polymer backbones made up catenated Ge atoms. Within the current contribution we report the preparation of a germanium polyethylene analogue, polydihydrogermane (GeH₂)_n, through two easy approaches that contain topotactic deintercalation of Ca ions from the CaGe Zintl part.

 

The ensuing (GeH₂)_n possesses morphologically dependent chemical and digital properties and thermally decomposes to yield amorphous hydrogenated Ge. We additionally present that the ensuing (GeH₂)_n supplies a platform from which functionalized polygermanes may be ready through thermally induced hydrogermylation-mediated pendant group substitution.

 

Coarse grained simulation of the aggregation and construction management of polyethylene nanocrystals

 

Polyethylene (PE) telechelics with carboxylate purposeful teams at each ends have been proven to assemble into hexagonal nanocrystal platelets with a peak outlined by their chain size in primary CsOH-solution. On this coarse grained (CG) simulation research we present how properties of the purposeful teams alter the aggregation and crystallization conduct of these telechelics. Systematic variation of the parameters of the CG mannequin confirmed that vital components which management nanoparticle stability and construction are the PE chain size and the hydrophilicity and the steric demand of the top teams.

To characterize the aggregation course of we analyzed the quantity and measurement of the obtained aggregates in addition to intramolecular order and intermolecular alignment of the polymer chains. By comparability of CG and atomistic simulation knowledge, it could possibly be proven that atomistic simulations representing completely different chemical methods may be emulated with particular, completely different CG parameter units. Thus, the outcomes from the (generic) CG simulation fashions can be utilized to clarify the impact of various head teams and completely different counterions on the aggregation of PE telechelics and the order of the obtained nanocrystals.

 

Modelling the visible response to an OUReP retinal prosthesis with photoelectric dye coupled to polyethylene movie

 

Goal: Retinal prostheses have been developed to revive imaginative and prescient in blind sufferers affected by ailments like retinitis pigmentosa.

 

Method: A brand new kind of retinal prosthesis known as the Okayama College-type Retinal Prosthesis (OUReP) was developed by chemically coupling photoelectric dyes to a polyethylene movie floor. The prosthesis works by passively producing an electrical potential when stimulated by mild. Nonetheless, the neurophysiological mechanism of how OUReP stimulates the degenerated retina is unknown.

 

Fundamental outcomes: Right here, we discover how the OUReP impacts retinal tissues utilizing a finite ingredient mannequin to resolve for the potential contained in the tissue and an lively Hodgkin-Huxley mannequin primarily based on rat imaginative and prescient to foretell the corresponding retinal bipolar response.

 

Significance: We present that the OUReP is probably going able to eliciting responses in retinal bipolar cells essential to generate imaginative and prescient beneath most ambient circumstances.

 

Chitosan-Functionalized Recycled Polyethylene Terephthalate Nanofibrous Membrane for Sustainable On-Demand Oil-Water Separation

 

The preservation of marine ecosystems is without doubt one of the most extreme challenges at current. Particularly, oil-water separation from oil spills and oily wastewater is vital. Because of this, a low-cost, efficient, and sustainable polymeric resolution is in excessive demand. On this work, a controlled-wettability membrane for selective separation of oil-water mixtures and emulsions is developed. The nanofibrous membrane is ready through a facile and cost-effective electrospinning method utilizing environmentally sustainable supplies, reminiscent of recycled polyethylene terephthalate and chitosan.

The impact of various concentrations of chitosan on the morphology, chemical composition, mechanical properties, wettability, and separation efficiency of the membrane is evaluated. The membranes exhibited underoil superhydrophobic and underwater superoleophobic conduct, which is important to carry out the selective separation. Actually, the designed filter has aggressive antifouling properties (oil intrusion strain > 45 kPa) and confirmed excessive heavy- and light-oil/water separation efficiencies (>95%) each for emulsions and immiscible mixtures.

 

In vitro bio-interaction responses and hemocompatibility of Nano-based Linear Low-Density Polyethylene Polymer Embedded with Heterogeneous TiO ₂/ZnO Nanocomposites for biomedical functions

 

An progressive nano-base polymer that scavenges radicals and reactive oxygen species reveals potential antibacterial properties, that are essential within the biomedical subject, significantly in decreasing nosocomial infections. Nonetheless, the security of this nano-based polymer, which has direct contact with the human system, has not been totally understood. The current research investigated the cytocompatibility and hemocompatibility responses of linear low-density polyethylene polymer (LLDPE) embedded with distinction ratios of heterogeneous TiO₂/ZnO nanocomposites.

Publicity of the blood and fibroblast cells to LLDPE/100Z and LLDPE/25T75Z/10% nanocomposite movies for 48 and 72 h decreased their viability by lower than 40%, in contrast with LLDPE, LLDPE/100T and LLDPE/25T75Z/5% nanocomposite movies. It additionally offered doable mobile harm and cytotoxicity, which was supported by the findings from the numerous launch of extracellular lactate dehydrogenase (LDH) profiles and cell survival assay Additional commentary utilizing an electron microscope revealed that LLDPE movies with heterogeneous 25T75Z/5% promoted cell adhesion.

Furthermore, no hemolysis was detected in all ratios of heterogeneous TiO₂/ZnO nanocomposite in LLDPE movie because it was lower than 0.2%, suggesting that these supplies have been hemocompatible. This research on LLDPE movie with heterogeneous TiO₂/ZnO nanocomposites demonstrated favorable biocompatible properties that have been important for superior biomedical polymer software in a hospital setting.

 

Synthesis of novel polymeric nanoparticles (methoxy-polyethylene glycol-chitosan/hyaluronic acid) containing 7-ethyl-10-hydroxycamptothecin for colon most cancers remedy: in vitro, ex vivo and in vivo investigation

The purpose of the present research was to focus on 7-ethyl-10-hydroxycamptothecin (SN38) orally to colon tumours by synthesizing a concentrating on polymer. To attain the optimum supply for SN38, initially methoxy-polyethylene glycol (mPEG)-chitosan was synthesized after which nanoparticles have been developed by ionic gelation between mPEG-chitosan and hyaluronic acid as a ligand for cell-surface glycoprotein CD44 receptor. The SN38 was loaded in nanoparticles (SN38-NPs) utilizing the non-covalent bodily adsorption methodology. The scale of the optimized SN38-NPs was 226.7 nm, encapsulation effectivity was 89.23% and drug content material was 7.98 ± 0.54% within the optimum formulation. The attachment of mPEG to chitosan was confirmed by proton nuclear magnetic resonance.

The outcomes of differential scanning calorimetry and Fourier transforms infra-red evaluation indicated that SN38 existed in amorphous type and purposeful teams of SN38 protected within the formulations which could possibly be an indication of appropriate encapsulation of SN38 in SN38-NPs. In vitro research indicated that SN38-NPs have been stronger towards the most cancers cells than free SN38. The mobile uptake of SN38-NPs improved as much as 1.6-fold towards human colorectal adenocarcinoma (Caco-2) cells. Furthermore, SN38-NPs remarkably demonstrated superior anti-tumor efficacy in opposite to pure SN38. This implies the benefit of SN38-NPs as a potent oral drug service which could possibly be additional explored for medical investigations.

In-Aircraft Shear Power of Single-Lap Co-Cured Joints of Self- einforced Polyethylene Composites 

The current research introduces the evaluation of single-lap co-cured joints of thermoplastic self-reinforced composites made with reprocessed low-density polyethylene (LDPE) and strengthened by ultra-high-molecular-weight polyethylene (UHMWPE) fibers, together with a micromechanical evaluation of its constituents. A set of optimum processing circumstances for manufacturing these joints by hot-press is proposed by a design of experiment utilizing the response floor methodology to maximise their in-plane shear power by carrying tensile checks on co-cured tapes.

Optimum processing circumstances have been discovered at 1 bar, 115 °C, and 300 s, yielding joints with 6.88 MPa of shear power. The shear failure is mostly preceded by a number of debonding-induced longitudinal cracks each inside and out of doors the joint attributable to gathered transversal stress. This composite demonstrated to be an attention-grabbing structural materials to be extra broadly utilized in trade, possessing extraordinarily elevated particular mechanical properties, progressive harm of co-cured joints (thus avoiding unannounced catastrophic failures) and supreme recyclability.

 

PEG Antibody / Polyethylene Glycol
R20194BTN-50UG	NSJ Bioreagents	50ug	EUR 489

Polyethylene Glycol (PEG) CLIA Kit
20-abx490560	Abbexa	EUR 11090.40 EUR 5904.00 EUR 1356.00	10 × 96 tests 5 × 96 tests 96 tests

General Polyethylene Glycol (PEG) ELISA Kit
CEX163Ge-10x96wellstestplate	Cloud-Clone	10x96-wells test plate	EUR 7248.6
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Polyethylene Glycol (PEG) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

General Polyethylene Glycol (PEG) ELISA Kit
CEX163Ge-1x48wellstestplate	Cloud-Clone	1x48-wells test plate	EUR 702.12
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Polyethylene Glycol (PEG) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

General Polyethylene Glycol (PEG) ELISA Kit
CEX163Ge-1x96wellstestplate	Cloud-Clone	1x96-wells test plate	EUR 951.6
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Polyethylene Glycol (PEG) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

General Polyethylene Glycol (PEG) ELISA Kit
CEX163Ge-5x96wellstestplate	Cloud-Clone	5x96-wells test plate	EUR 3922.2
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Polyethylene Glycol (PEG) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

General Polyethylene Glycol (PEG) ELISA Kit
4-CEX163Ge	Cloud-Clone	EUR 7309.20 EUR 3862.80 EUR 952.80	10 plates of 96 wells 5 plates of 96 wells 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of General Polyethylene Glycol (PEG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

General Polyethylene Glycol ELISA Kit (PEG)
RK00701	Abclonal	96 Tests	EUR 687.6

BSA Conjugated Polyethylene Glycol (PEG)
4-CPX163Ge11	Cloud-Clone	EUR 496.32 EUR 256.80 EUR 1531.20 EUR 590.40 EUR 1060.80 EUR 408.00 EUR 3648.00	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Pan-species Polyethylene Glycol expressed in: E.coli

OVA Conjugated Polyethylene Glycol (PEG)
4-CPX163Ge21	Cloud-Clone	EUR 496.32 EUR 256.80 EUR 1531.20 EUR 590.40 EUR 1060.80 EUR 408.00 EUR 3648.00	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Pan-species Polyethylene Glycol expressed in: E.coli

Polyethylene Glycol (PEG) Antibody (Biotin)
abx021052-005mg	Abbexa	0.05 mg	EUR 978

Polyethylene Glycol (PEG) Protein (BSA)
20-abx651925	Abbexa	EUR 693.60 EUR 309.60 EUR 2064.00 EUR 828.00 EUR 510.00	100 ug 10 ug 1 mg 200 ug 50 ug

Polyethylene Glycol (PEG) Protein (OVA)
20-abx651926	Abbexa	EUR 693.60 EUR 309.60 EUR 2064.00 EUR 828.00 EUR 510.00	100 ug 10 ug 1 mg 200 ug 50 ug

ELISA kit for General PEG (Polyethylene Glycol)
ELK8264	ELK Biotech	1 plate of 96 wells	EUR 446.4
Description: A competitive Inhibition ELISA kit for detection of Polyethylene Glycol from General in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Polyethylene Glycol (PEG) Polyclonal Antibody (Pan-species)
4-PAX163Ge01	Cloud-Clone	EUR 303.60 EUR 3138.00 EUR 778.80 EUR 382.80 EUR 260.40	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Pan-species Polyethylene Glycol (PEG)

Polyethylene glycol 1500
GK2627-100G	Glentham Life Sciences	100 g	EUR 52.8

Polyethylene glycol 1500
GK2627-1KG	Glentham Life Sciences	1 kg	EUR 74.4

Polyethylene glycol 1500
GK2627-500G	Glentham Life Sciences	500 g	EUR 58.8

Polyethylene glycol 1000
GC0081-100G	Glentham Life Sciences	100 g	EUR 55.2

Polyethylene glycol 8000
GC0902-100G	Glentham Life Sciences	100 g	EUR 57.6

Polyethylene glycol 8000
GC0902-1KG	Glentham Life Sciences	1 kg	EUR 92.4

Polyethylene glycol 8000
GC0902-500G	Glentham Life Sciences	500 g	EUR 74.4

Polyethylene glycol 6000
GC2342-100G	Glentham Life Sciences	100 g	EUR 52.8

Polyethylene glycol 6000
GC2342-1KG	Glentham Life Sciences	1 kg	EUR 74.4

Polyethylene glycol 6000
GC2342-500G	Glentham Life Sciences	500 g	EUR 58.8

Polyethylene glycol 400
GC3481-100G	Glentham Life Sciences	100 g	EUR 49.2

Polyethylene glycol 400
GC3481-1KG	Glentham Life Sciences	1 kg	EUR 78

Polyethylene glycol 400
GC3481-250G	Glentham Life Sciences	250 g	EUR 55.2

Polyethylene glycol 400
GC3481-500G	Glentham Life Sciences	500 g	EUR 63.6

Polyethylene glycol 400
GC3481-5KG	Glentham Life Sciences	5 kg	EUR 183.6

Polyethylene glycol 300
GC9998-100G	Glentham Life Sciences	100 g	EUR 48

Polyethylene glycol 300
GC9998-1KG	Glentham Life Sciences	1 kg	EUR 74.4

Polyethylene glycol 300
GC9998-250G	Glentham Life Sciences	250 g	EUR 52.8

Polyethylene glycol 300
GC9998-500G	Glentham Life Sciences	500 g	EUR 62.4

Polyethylene glycol 300
GC9998-5KG	Glentham Life Sciences	5 kg	EUR 170.4

Polyethylene glycol 4000
GX6931-100G	Glentham Life Sciences	100 g	EUR 52.8

Polyethylene glycol 4000
GX6931-1KG	Glentham Life Sciences	1 kg	EUR 74.4

Polyethylene glycol 4000
GX6931-500G	Glentham Life Sciences	500 g	EUR 58.8

Polyethylene Glycol - 200
S-3126	Scientific Laboratory Supplies	1ML	EUR 38.76

Polyethylene Glycol - 400
S-3127	Scientific Laboratory Supplies	1ML	EUR 77.52

Polyethylene Glycol - 600
S-3128	Scientific Laboratory Supplies	1ML	EUR 38.76

Polyethylene Glycol (PEG) Polyclonal Antibody (Pan-species), APC
4-PAX163Ge01-APC	Cloud-Clone	EUR 426.00 EUR 4102.80 EUR 1137.60 EUR 544.80 EUR 268.80	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Pan-species Polyethylene Glycol (PEG). This antibody is labeled with APC.

Polyethylene Glycol (PEG) Polyclonal Antibody (Pan-species), Biotinylated
4-PAX163Ge01-Biotin	Cloud-Clone	EUR 381.60 EUR 3078.00 EUR 903.60 EUR 469.20 EUR 266.40	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Pan-species Polyethylene Glycol (PEG). This antibody is labeled with Biotin.

Polyethylene Glycol (PEG) Polyclonal Antibody (Pan-species), Cy3
4-PAX163Ge01-Cy3	Cloud-Clone	EUR 518.40 EUR 5420.40 EUR 1467.60 EUR 676.80 EUR 308.40	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Pan-species Polyethylene Glycol (PEG). This antibody is labeled with Cy3.

Polyethylene Glycol (PEG) Polyclonal Antibody (Pan-species), FITC
4-PAX163Ge01-FITC	Cloud-Clone	EUR 364.80 EUR 3306.00 EUR 933.60 EUR 459.60 EUR 238.80	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Pan-species Polyethylene Glycol (PEG). This antibody is labeled with FITC.

Polyethylene Glycol (PEG) Polyclonal Antibody (Pan-species), HRP
4-PAX163Ge01-HRP	Cloud-Clone	EUR 388.80 EUR 3574.80 EUR 1005.60 EUR 492.00 EUR 252.00	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Pan-species Polyethylene Glycol (PEG). This antibody is labeled with HRP.

Polyethylene Glycol (PEG) Polyclonal Antibody (Pan-species), PE
4-PAX163Ge01-PE	Cloud-Clone	EUR 364.80 EUR 3306.00 EUR 933.60 EUR 459.60 EUR 238.80	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Pan-species Polyethylene Glycol (PEG). This antibody is labeled with PE.

Polyethylene Glycol (PEG) Polyclonal Antibody (Pan-species), APC-Cy7
4-PAX163Ge01-APC-Cy7	Cloud-Clone	EUR 708.00 EUR 8061.60 EUR 2132.40 EUR 945.60 EUR 393.60	100ul 10ml 1ml 200ul 20ul
Description: A Rabbit polyclonal antibody against Pan-species Polyethylene Glycol (PEG). This antibody is labeled with APC-Cy7.

Mouse Anti-PEG mAb [Anti-Polyethylene glycol monoclonal antibody]
57000	AAT Bioquest	50 ug	EUR 199

HSP70 ELISA Kit (High-Sensitivity)
EK7109	BosterBio	96wells/kit, with removable strips.	EUR 909.6

HSP70 ELISA Kit (High-Sensitivity)
abx259904-96well	Abbexa	96 well	EUR 1299.6

HSP70 ELISA Kit (High-Sensitivity)
SKT-108-480	Stressmarq	5 plates of 96 wells	EUR 3242.4
Description: Sandwich ELISA kit used for quantitate HSP70 concentration in Serum, Plasma, Cell Lysates, Tissue samples from Human, Monkey, Dog, Rat, Mouse

HSP70 ELISA Kit (High-Sensitivity)
SKT-108-96	Stressmarq	1 plate of 96 wells	EUR 822
Description: Sandwich ELISA kit used for quantitate HSP70 concentration in Serum, Plasma, Cell Lysates, Tissue samples from Human, Monkey, Dog, Rat, Mouse

D-alpha-Tocopherol polyethylene glycol succinate
GK2339-25G	Glentham Life Sciences	25 g	EUR 180

D-alpha-Tocopherol polyethylene glycol succinate
GK2339-5G	Glentham Life Sciences	5 g	EUR 84

OVAL High Sensitivity ELISA Kit (OKCD01353)
OKCD01353	Aviva Systems Biology	96 Wells	EUR 715.2
Description: Description of target: Non-inhibitory serpin. Storage protein of egg white.;Species reactivity: pan-species;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: <28 pg/mL

Human EGF ELISA Kit (High Sensitivity)
RK00024HS	Abclonal	96 Tests	EUR 704.4

Human Anti-PEG IgG ELISA Kit, 96 tests, Quantitative
PEG-010	Alpha Diagnostics	1 Kit	EUR 854.4

Human Anti-PEG IgM ELISA Kit, 96 tests, Quantitative
PEG-020	Alpha Diagnostics	1 Kit	EUR 854.4

Mouse Anti-PEG IgG ELISA Kit, 96 tests, Quantitative
PEG-030	Alpha Diagnostics	1 Kit	EUR 854.4

Mouse Anti-PEG IgM ELISA Kit, 96 tests, Quantitative
PEG-040	Alpha Diagnostics	1 Kit	EUR 854.4

Monkey Anti-PEG IgG ELISA Kit, 96 tests, Quantitative
PEG-050	Alpha Diagnostics	1 Kit	EUR 854.4

Monkey Anti-PEG IgM ELISA Kit, 96 tests, Quantitative
PEG-060	Alpha Diagnostics	1 Kit	EUR 854.4

Rat Anti-PEG IgG ELISA Kit, 96 tests, Quantitative
PEG-070	Alpha Diagnostics	1 Kit	EUR 854.4

Rat Anti-PEG IgM ELISA Kit, 96 tests, Quantitative
PEG-080	Alpha Diagnostics	1 Kit	EUR 854.4

ChromaFlash High-Sensitivity ChIP Kit
P-2027-24	EpiGentek	24 Reactions	EUR 338.8

ChromaFlash High-Sensitivity ChIP Kit
P-2027-48	EpiGentek	48 Reactions	EUR 512.6

ChromaFlash High-Sensitivity ChIP Kit
P-2027	EpiGentek	EUR 771.66 EUR 338.80 EUR 512.60	48 Reactions 24 Reactions 48 Reactions

Poly(ethylene glycol) methyl ether (mPEG) Molecular Weight: 20000
PEG-20K	Alpha Diagnostics	100 mg	EUR 270

High-sensitivity Human Growth Hormone ELISA Kit
DEIA449	Creative Diagnostics	96T	EUR 814.8
Description: Thishigh-sensitivity Human Growth Hormone ELISA Kit is to be used for the invitro quantitative determination of human growth hormone (hGH) concentrationsin serum.

Rat High Sensitivity Insulin (INS) ELISA Kit
abx363835-96tests	Abbexa	96 tests	EUR 943.2

IGF1 High Sensitivity ELISA Kit (Dog) (OKCD01300)
OKCD01300	Aviva Systems Biology	96 Wells	EUR 1123.2
Description: Description of target: The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca2+-dependent exocytosis of IGF1 is required for sensory perception of smell in the olfactory bulb. Acts as a ligand for IGF1R. Binds to the alpha subunit of IGF1R, leading to the activation of the intrinsic tyrosine kinase activity which autophosphorylates tyrosine residues in the beta subunit thus initiatiating a cascade of down-stream signaling events leading to activation of the PI3K-AKT/PKB and the Ras-MAPK pathways. Binds to integrins ITGAV:ITGB3 and ITGA6:ITGB4. Its binding to integrins and subsequent ternary complex formation with integrins and IGFR1 are essential for IGF1 signaling. Induces the phosphorylation and activation of IGFR1, MAPK3/ERK1, MAPK1/ERK2 and AKT1.;Species reactivity: Dog;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 6.5 pg/mL

Il10 High Sensitivity ELISA Kit (Mouse) (OKCD01301)
OKCD01301	Aviva Systems Biology	96 Wells	EUR 1044
Description: Description of target: Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. ;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.43 pg/mL

Il1a High Sensitivity ELISA Kit (Mouse) (OKCD01303)
OKCD01303	Aviva Systems Biology	96 Wells	EUR 1090.8
Description: Description of target: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. ;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 1.03 pg/mL

Il1a High Sensitivity ELISA Kit (Rat) (OKCD01304)
OKCD01304	Aviva Systems Biology	96 Wells	EUR 888
Description: Description of target: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. ;Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 3.8 pg/mL

IL2 High Sensitivity ELISA Kit (Human) (OKCD01305)
OKCD01305	Aviva Systems Biology	96 Wells	EUR 856.8
Description: Description of target: Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. ;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.51 pg/mL

IL6 High Sensitivity ELISA Kit (Bovine) (OKCD01306)
OKCD01306	Aviva Systems Biology	96 Wells	EUR 1123.2
Description: Description of target: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.;Species reactivity: Bovine;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.45 pg/mL

IL6 High Sensitivity ELISA Kit (Goat) (OKCD01307)
OKCD01307	Aviva Systems Biology	96 Wells	EUR 1248
Description: Description of target: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.;Species reactivity: Goat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.138 pg/mL

IL6 High Sensitivity ELISA Kit (Human) (OKCD01308)
OKCD01308	Aviva Systems Biology	96 Wells	EUR 777.6
Description: Description of target: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation. ;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.35 pg/mL

IL6 High Sensitivity ELISA Kit (Sheep) (OKCD01309)
OKCD01309	Aviva Systems Biology	96 Wells	EUR 1232.4
Description: Description of target: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.;Species reactivity: Sheep;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.46 pg/mL

Il6 High Sensitivity ELISA Kit (Rat) (OKCD01310)
OKCD01310	Aviva Systems Biology	96 Wells	EUR 730.8
Description: Description of target: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.;Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.47 pg/mL

IL8 High Sensitivity ELISA Kit (Human) (OKCD01311)
OKCD01311	Aviva Systems Biology	96 Wells	EUR 777.6
Description: Description of target: IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 1.7 pg/mL

LN High Sensitivity ELISA Kit (Human) (OKCD01312)
OKCD01312	Aviva Systems Biology	96 Wells	EUR 997.2
Description: Description of target: ;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 11.5 pg/mL

MMP1 High Sensitivity ELISA Kit (Rabbit) (OKCD01313)
OKCD01313	Aviva Systems Biology	96 Wells	EUR 1075.2
Description: Description of target: Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. ;Species reactivity: Rabbit;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 11.5 pg/mL

MMP13 High Sensitivity ELISA Kit (Human) (OKCD01314)
OKCD01314	Aviva Systems Biology	96 Wells	EUR 997.2
Description: Description of target: Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.1;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 12.1 pg/mL

Mmp13 High Sensitivity ELISA Kit (Mouse) (OKCD01315)
OKCD01315	Aviva Systems Biology	96 Wells	EUR 1012.8
Description: Description of target: Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: < 6.3 pg/mL

NGF High Sensitivity ELISA Kit (Human) (OKCD01316)
OKCD01316	Aviva Systems Biology	96 Wells	EUR 872.4
Description: Description of target: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.97 pg/mL

Cxcl12 High Sensitivity ELISA Kit (Rat) (OKCD01317)
OKCD01317	Aviva Systems Biology	96 Wells	EUR 1075.2
Description: Description of target: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Impairs regulatory T-cells (Treg) function in individuals with rheumatoid arthritis via FOXP3 dephosphorylation. Upregulates the expression of protein phosphatase 1 (PP1), which dephosphorylates the key 'Ser-418' residue of FOXP3, thereby inactivating FOXP3 and rendering Treg cells functionally defective. Key mediator of cell death in the anticancer action of BCG-stimulated neutrophils in combination with DIABLO/SMAC mimetic in the RT4v6 bladder cancer cell line.;Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 5.5 pg/mL

TNF High Sensitivity ELISA Kit (Human) (OKCD01318)
OKCD01318	Aviva Systems Biology	96 Wells	EUR 856.8
Description: Description of target: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Impairs regulatory T-cells (Treg) function in individuals with rheumatoid arthritis via FOXP3 dephosphorylation. Upregulates the expression of protein phosphatase 1 (PP1), which dephosphorylates the key 'Ser-418' residue of FOXP3, thereby inactivating FOXP3 and rendering Treg cells functionally defective. Key mediator of cell death in the anticancer action of BCG-stimulated neutrophils in combination with DIABLO/SMAC mimetic in the RT4v6 bladder cancer cell line.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.49 pg/mL

IFNB High Sensitivity ELISA Kit (Chicken) (OKCD01319)
OKCD01319	Aviva Systems Biology	96 Wells	EUR 1075.2
Description: Description of target: Has antiviral activities. ;Species reactivity: Chicken;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 1.16 pg/mL