micchem

Inhibitor of DNA binding 2 (Id2) mediates microtubule polymerization in the brain by regulating αK40 acetylation of α-tubulin

Acetylation of α-tubulin lysine 40 (αK40) contributes to microtubule (MT) stability and is crucial for neuronal improvement and performance, whereas extreme αK40 deacetylation is noticed in neurodegenerative problems together with Alzheimer’s illness (AD). Right here we recognized inhibitor of DNA binding 2 (Id2) as a novel MT-binding associate that interacts with α-tubulin and enhances αK40 acetylation, resulting in MT polymerization within the neurons. Commensurate with our discovering that the low ranges of Id2 expression together with a decreased αK40 acetylation within the postmortem human AD affected person and 5X-FAD, AD mannequin mice mind, Id2 upregulation within the hippocampus of 5X-FAD, which exhibit excessive ranges of Sirt2 expression, elevated αK40 acetylation and reconstitutes axon progress. Therefore our research means that Id2 is essential for sustaining MT stability throughout neural improvement and the potential of Id2 to counteract pathogenic Sirt2 exercise in AD.

Block copolymers primarily based on ethylene and methacrylates utilizing a mixture of catalytic chain switch polymerisation (CCTP) and radical polymerization

Two scalable polymerization strategies are utilized in mixture for the synthesis of ethylene and methacrylate block copolymers. ω-Unsaturated methacrylic oligomers (MMA n ) produced by catalytic chain switch (co)polymerisation (CCTP) of methyl methacrylate (MMA) and methacrylic acid (MAA) are used as reagents within the radical polymerization of ethylene (E) in dimethyl carbonate solvent beneath comparatively gentle situations (80 bar, 70°C). Kinetic measurements and analyses of the produced copolymers by dimension exclusion chromatography (SEC) and a mixture of nuclear magnetic resonance (NMR) strategies point out that MMA n is concerned in a degradative chain switch course of ensuing within the formation of (MMA) n – b -PE block copolymers. Molecular modelling carried out by DFT helps the general reactivity scheme and noticed selectivities. The impact of MMA n molar mass and composition can also be studied. The block copolymers have been characterised by differential scanning calorimetry (DSC) and their bulk behaviour studied by SAXS/WAXS evaluation.

Fabrication of hydrophilic zwitterionic microspheres by way of inverse suspension polymerization for the enrichment of N-glycopeptides

A form of zwitterionic microsphere was ready by way of one-step inverse suspension polymerization using 3-[N,N-dimethyl-[2-(2-methylpropyl-2-enyloxy) ethyl] ammonium] propane-1-sulfonate (MSA) and N,N-methylene bisacrylamide (BIS) because the precursors. The preparation situations have been fastidiously investigated and optimized by regulating the content material of complete monomers, ratio of MSA to BIS, ratio of water to grease, and content material of stabilizer.
The properties of microspheres have been characterised by helium ion microscopy (HIM), Fourier remodel infrared spectroscopy (FT-IR), X-ray photoelectron spectroscopy (XPS), N2 adsorption/desorption measurement, and water contact angle measurement.
The particle dimension of ensuing polydisperse microspheres ranged from 15-25 μm, exhibiting excessive particular floor space of 138 m2 g-1. Owing to nice hydrophilicity, the ensuing zwitterionic microspheres may very well be straight used as hydrophilic interplay chromatography (HILIC) sorbent to complement glycopeptides from biosamples with none chemical modification. A complete of 19 N-glycopeptides was enriched from 10 μg of IgG digest.
In addition to, as much as 383 N-glycopeptides and 224 N-glycosylation websites have been unambiguously recognized from 2 μL of human serum digest by cLC-MS/MS after enrichment with zwitterionic microspheres, indicating their nice enrichment efficiency to N-glycopeptides. The method of getting ready hydrophilic zwitterionic microspheres incorporates just one synthesis response and is appropriate for large-scale preparation.

Mussel-inspired adhesive antioxidant antibacterial hemostatic composite hydrogel wound dressing by way of photo-polymerization for contaminated pores and skin wound therapeutic

With the growing prevalence of drug-resistant bacterial infections and the gradual therapeutic of chronically contaminated wounds, the event of latest antibacterial and accelerated wound therapeutic dressings has develop into a severe problem. With a purpose to remedy this drawback, we developed photo-crosslinked multifunctional antibacterial adhesive anti-oxidant hemostatic hydrogel dressings primarily based on polyethylene glycol monomethyl ether modified glycidyl methacrylate functionalized chitosan (CSG-PEG), methacrylamide dopamine (DMA) and zinc ion for disinfection of drug-resistant micro organism and selling wound therapeutic. The mechanical properties, rheological properties and morphology of hydrogels have been characterised, and the biocompatibility of those hydrogels was studied via cell compatibility and blood compatibility exams.
These hydrogels have been examined for the in vitro blood-clotting potential of entire blood and confirmed good hemostatic potential within the mouse liver hemorrhage mannequin and the mouse-tail amputation mannequin. As well as, it has been confirmed that the multifunctional hydrogels have good inherent antibacterial properties in opposition to Methicillin-resistant Staphylococcus aureus (MRSA). Within the full-thickness pores and skin defect mannequin contaminated with MRSA, the wound closure ratio, thickness of granulation tissue, variety of collagen deposition, regeneration of blood vessels and hair follicles have been measured.
The inflammation-related cytokines (CD68) and angiogenesis-related cytokines (CD31) expressed throughout pores and skin regeneration have been studied. All outcomes point out that these multifunctional antibacterial adhesive hemostatic hydrogels have higher therapeutic results than commercially out there Tegaderm™ Movie, revealing that they’ve develop into promising different within the therapeutic of contaminated wounds.

Revealing Polymerization Kinetics with Colloidal Dipatch Particles

Restricted-valency colloidal particles can self-assemble into polymeric buildings analogous to molecules. Whereas their structural equilibrium properties have attracted extensive consideration, perception into their dynamics has confirmed difficult. Right here, we examine the polymerization dynamics of semiflexible polymers in 2D by direct statement of assembling divalent particles, bonded by essential Casimir forces.
The reversible essential Casimir power creates dwelling polymerization situations with tunable chain dissociation, affiliation, and bending rigidity. We discover that in contrast to dilute polymers that present exponential dimension distributions in wonderful settlement with Flory concept, concentrated samples exhibit arrest of rotational and translational diffusion because of a steady isotropic-to-nematic transition in 2D, slowing down the expansion kinetics.
These results are circumvented by the addition of higher-valency particles, cross linking the polymers into networks. Our outcomes connecting polymer flexibility, polymer interactions, and the peculiar isotropic-nematic transition in 2D provide perception into the polymerization processes of artificial two-dimensional polymers and biopolymers at membranes and interfaces.
micchem
micchem

Controllable Frontal Polymerization and Spontaneous Patterning Enabled by Part-Altering Particles

Frontal polymerization supplies a fast, financial, and environmentally pleasant methodology to fabricate thermoset polymers and composites. Regardless of its effectivity and decreased environmental affect, the manufacturing methodology is underutilized as a result of restricted elementary understanding of its dynamic management. This work experiences the management and patterning of the entrance propagation in a dicyclopentadiene resin by immersion of phase-changing polycaprolactone particles.
Predictive and designed patterning is enabled by multiphysical numerical analyses, which reveal that the interaction between endothermic part transition, exothermic chemical response, and warmth change govern the temperature, velocity, and propagation path of the entrance by way of two completely different interplay regimes. To sample the entrance, one can range the dimensions and spacing between the particles and enhance the variety of propagating fronts, leading to tunable bodily patterns shaped because of entrance separation and merging close to the particles. Each single- and double-frontal polymerization experiments in an open mildew are carried out.
The outcomes affirm the front-particle interplay mechanisms and the shapes of the patterns explored numerically. The current research provides a elementary understanding of frontal polymerization within the presence of heat-absorbing second-phase supplies and proposes a possible one-step manufacturing methodology for exactly patterned polymeric and composite supplies with out masks, molds, or printers.

HS-PEG-NHS,400

33-HE003023-400
  • EUR 534.00
  • EUR 1480.80
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

SH-PEG-Biotin,400

33-HE003041-400
  • EUR 740.40
  • EUR 2101.20
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

NH2-PEG-COOH,400

33-HE005017-400
  • EUR 430.80
  • EUR 1170.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

SH-PEG-SH,400

33-HO003003-400
  • EUR 310.80
  • EUR 812.40
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

COOH-PEG-COOH,400

33-HO017017-400
  • EUR 200.40
  • EUR 478.80
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

SC-PEG-SC,400

33-HO023023-400
  • EUR 200.40
  • EUR 478.80
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

SH-PEG-NH-Methoxyphenone,400

33-HE003071-400
  • EUR 622.80
  • EUR 1658.40
  • 100mg
  • 500mg
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

mPEG-CH3?400

33-MF001049-400
  • EUR 279.60
  • EUR 718.80
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

DSPE-PEG-NH2

33-LP096005-400
  • EUR 829.20
  • EUR 2367.60
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

HO-PEG-NH2,400

33-HE002005-400
  • EUR 504.00
  • EUR 1392.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

SH-PEG-NH2,400

33-HE003005-400
  • EUR 1909.20
  • EUR 681.60
  • 5g
  • g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

MAL-PEG-NH2,400

33-HE022005-400
  • EUR 622.80
  • EUR 1747.20
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

NH2-PEG-NH2,400

33-HO005005-400
  • EUR 282.00
  • EUR 726.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

FITC-PEG-Alkyne,400

FL044007-400-100mg 100mg
EUR 681.6
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

FA-PEG-NHS,400

HE057023-400-100mg 100mg
EUR 452.4
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

OH-PEG-OH,400

HO002002-400-10g 10g
EUR 367.2
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

Turbidity Std Ratio 400 NTU

CRSR-400-100 100ML
EUR 191.52

Turbidity Std Ratio 400 NTU

CRSR-400-500 500ML
EUR 399

Turbidity Std Non Ratio 400 NTU

CRS-400-100 100ML
EUR 191.52

Turbidity Std Non Ratio 400 NTU

CRS-400-500 500ML
EUR 399

Sulfur 400 ug/g (400 PPM) for AA and ICP 100 grams in no.2 Diesel Fuel

SDFS-400-Y 100ML
EUR 102.6

Anti-Alexa Fluor 647 Antibody | M647-65A-400

M647-65A-400 1.0 mg
EUR 379
Description:

Anti-Alexa Fluor 647 Antibody | M647-65A-400 | Immunology Consultants Laboratory

Host: Mouse

Format: Unconjugated AP

Product Type: Primary Antibody

Antibody Clonality: Monoclonal

Polyethyleneglycol 400, 100 % v/v, 100 ML

M-CSS-252 100 ml
EUR 77
Description: Polyethyleneglycol 400, 100 % v/v, 100 ML

TruStrip Sample Transfer Strips, 400-ul, 50/Pk (without sample tracking dye)

STS-400-50 1 Pk Ask for price

TruStrip Sample Transfer Strips, 400-ul, 50/Pk (with sample tracking dye)

STSD-400-50 1 Pk Ask for price

Ficoll 400

F760014 25g
EUR 108.02

Polysucrose 400

abx082061-10g 10 g
EUR 226.8

Ficoll 400

abx082174-50g 50 g
EUR 326.4

Polysucrose 400

GC7257-100G 100 g
EUR 274.8

Polysucrose 400

GC7257-250G 250 g
EUR 514.8

Polysucrose 400

GC7257-25G 25 g
EUR 122.4

ROX Reference Dye *50X fluorescence reference solution for PCR reactions*

400 5 mL
EUR 222

JBScreen Membrane 1 (PEG 400 to PEG 2000 MME based)

M-CS-301L 24 solutions
EUR 339
Description: JBScreen Membrane 1 (PEG 400 to PEG 2000 MME based)

JBScreen Classic 1 (PEG 400 to 3000 based)

M-CS-101L 24 solutions
EUR 204
Description: JBScreen Classic 1 (PEG 400 to 3000 based)

Indexed MicroMesh; box of 20 with 400 micron Diameter and 25 micron mesh Opening

M3-L18SP-400/25-IN1 20 MOUNTS
EUR 112
Description: Indexed MicroMesh; box of 20 with 400 micron Diameter and 25 micron mesh Opening

Polyethylene glycol 400

GC3481-100G 100 g
EUR 49.2

Polyethylene glycol 400

GC3481-1KG 1 kg
EUR 78

Polyethylene glycol 400

GC3481-250G 250 g
EUR 55.2

Polyethylene glycol 400

GC3481-500G 500 g
EUR 63.6

Polyethylene glycol 400

GC3481-5KG 5 kg
EUR 183.6

Anti-Hex (400)

YF-MA13442 100 ug
EUR 435.6
Description: Mouse monoclonal to Hex

Stomacher 400 EVO

MIX3004 EACH
EUR 4180.38

Stomacher 400 bags

MIX3102 PK500
EUR 61.56

Polyethylene Glycol - 400

S-3127 1ML
EUR 77.52

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B1

B-M3-400/25IN1-B1 20 MOUNT/BASE ASSEMBLIES
EUR 249
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B1

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B1A

B-M3-400/25IN1-B1A 20 MOUNT/BASE ASSEMBLIES
EUR 249
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B1A

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B3

B-M3-400/25IN1-B3 20 MOUNT/BASE ASSEMBLIES
EUR 249
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B3

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B3S

B-M3-400/25IN1-B3S 20 MOUNT/BASE ASSEMBLIES
EUR 249
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B3S

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B5

B-M3-400/25IN1-B5 20 MOUNT/BASE ASSEMBLIES
EUR 249
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B5

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B1

B-M3-400/25IN2-B1 20 MOUNT/BASE ASSEMBLIES
EUR 249
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B1

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B1A

B-M3-400/25IN2-B1A 20 MOUNT/BASE ASSEMBLIES
EUR 249
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B1A

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B3

B-M3-400/25IN2-B3 20 MOUNT/BASE ASSEMBLIES
EUR 249
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B3

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B3S

B-M3-400/25IN2-B3S 20 MOUNT/BASE ASSEMBLIES
EUR 249
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B3S

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B5

B-M3-400/25IN2-B5 20 MOUNT/BASE ASSEMBLIES
EUR 249
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B5

Histone H3 Peptide (residues 1-21) 

R-1003
  • EUR 267.06
  • EUR 78.10
  • EUR 140.80
  • 400 µl
  • 200 ul
  • 400 ul

Indexed MicroMesh; box of 20 with 400 micron Diameter and 25 micron mesh Opening, Square Openings

M3-L18SP-400/25-IN2 20 MOUNTS
EUR 112
Description: Indexed MicroMesh; box of 20 with 400 micron Diameter and 25 micron mesh Opening, Square Openings

MAP3K8 (Ab-400) Antibody

CSB-PA901361-
EUR 402
Description: A polyclonal antibody against MAP3K8 (Ab-400). Recognizes MAP3K8 (Ab-400) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:3000, IHC:1:50-1:100

MAP3K8 (Ab-400) Antibody

CSB-PA901361-100ul 100ul
EUR 379.2
Description: A polyclonal antibody against MAP3K8 (Ab-400). Recognizes MAP3K8 (Ab-400) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:3000, IHC:1:50-1:100

MAP3K8 (Ab-400) Antibody

33235-100ul 100ul
EUR 302.4

MAP3K8 (Ab-400) Antibody

33235-50ul 50ul
EUR 224.4

Tau (pS717 / 400) Antibody

abx218901-100ug 100 ug
EUR 526.8

Alu I unit: 400

YRALU1 1 vial Ask for price

Bcl I unit: 400

YRBCL1 1 vial Ask for price

Bsp1286 I unit: 400

YRBSP1286 1 vial Ask for price

Nco I unit: 400

YRNCO1 1 vial Ask for price

Not I unit: 400

YRNOT1 1 vial Ask for price

Ssp I unit: 400

YRSSP1 1 vial Ask for price

Seward Stomacher 400 Circulator

MIX3011 EACH
EUR 3642.3

400 Eco Bag Rack

MIX3016 EACH
EUR 80.94

Blender Bag 400+Closure

MIX3110 PK250
EUR 96.9

Blender Bag 400+Closure

MIX3111 PK250
EUR 70.68

Stomacher 400 Circulator Bags

MIX3150 PK500
EUR 51.3

Stomacher 400 Classic Bags

MIX3175 PK500
EUR 96.9

Stomacher 400 Circulator Bags

MIX3177 PK500
EUR 98.04

Stomacher 400 Bag Clip

SEW3116 PK200
EUR 258.78

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B1-R

B-M3-400/25IN1-B1-R 20 MOUNT/BASE ASSEMBLIES
EUR 339
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B1-R

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B1A-R

B-M3-400/25IN1-B1A-R 20 MOUNT/BASE ASSEMBLIES
EUR 339
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B1A-R

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B3-R

B-M3-400/25IN1-B3-R 20 MOUNT/BASE ASSEMBLIES
EUR 339
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B3-R

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B3S-R

B-M3-400/25IN1-B3S-R 20 MOUNT/BASE ASSEMBLIES
EUR 339
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B3S-R

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B5-R

B-M3-400/25IN1-B5-R 20 MOUNT/BASE ASSEMBLIES
EUR 339
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B5-R

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B1-R

B-M3-400/25IN2-B1-R 20 MOUNT/BASE ASSEMBLIES
EUR 339
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B1-R

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B1A-R

B-M3-400/25IN2-B1A-R 20 MOUNT/BASE ASSEMBLIES
EUR 339
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B1A-R

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B3-R

B-M3-400/25IN2-B3-R 20 MOUNT/BASE ASSEMBLIES
EUR 339
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B3-R

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B3S-R

B-M3-400/25IN2-B3S-R 20 MOUNT/BASE ASSEMBLIES
EUR 339
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B3S-R

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B5-R

B-M3-400/25IN2-B5-R 20 MOUNT/BASE ASSEMBLIES
EUR 339
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B5-R

Methoxy PEG Maleimide linear (MW: 10,000)

PEG-10K 100 mg
EUR 270

Methoxy PEG Maleimide lbranched (MW: 40,000)

PEG-40K 100 mg
EUR 270

Methoxy PEG Maleimide linear (MW: 5,000)

PEG-5K 100 mg
EUR 270

MAPT (Ab-717/400) Antibody

CSB-PA112612-
EUR 402
Description: A polyclonal antibody against MAPT (Ab-717/400). Recognizes MAPT (Ab-717/400) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

MAPT (Ab-717/400) Antibody

CSB-PA112612-100ul 100ul
EUR 379.2
Description: A polyclonal antibody against MAPT (Ab-717/400). Recognizes MAPT (Ab-717/400) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

Bromoacetyl resin (200-400 mesh)

D-2555.0001 1.0g
EUR 166.8

Bromoacetyl resin (200-400 mesh)

D-2555.0005 5.0g
EUR 529.2

MAP3K8 (Ab-400) Conjugated Antibody

C33235 100ul
EUR 476.4

Polyclonal SNX2 Antibody (aa350-400)

AMM07912G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human SNX2 (aa350-400). This antibody is tested and proven to work in the following applications:

DiagNano Silica Particles, 400 nm

DNG-B008 10 mL
EUR 670.8

100 G POLYSUCROSE 400, POWDER

61-196-RM 100 g/pk
EUR 307.2
Description: Specialty Media; Insect Media Products

500 G POLYSUCROSE 400, POWDER

61-196-RO 500 g/pk
EUR 608.4
Description: Specialty Media; Insect Media Products

Tau (Ab-717/400) Antibody

33223-100ul 100ul
EUR 302.4

Tau (Ab-717/400) Antibody

33223-50ul 50ul
EUR 224.4

Tau (Phospho-Ser717/400) Antibody

12486-100ul 100ul
EUR 302.4

Tau (Phospho-Ser717/400) Antibody

12486-50ul 50ul
EUR 224.4

Tau (Phospho- Ser717/400) Antibody

ABF8129 100 ug
EUR 525.6

9998 SCREW CAP 400/24

9998-24 12/pk
EUR 64.8
Description: General Apparatus; Stoppers

9999 CAP ONLY 400/24

9999-24 12/pk
EUR 60
Description: General Apparatus; Stoppers

Polyclonal NPY2R Antibody (aa350-400)

APR08798G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human NPY2R (aa350-400). This antibody is tested and proven to work in the following applications:

Polyclonal GHRHR Antibody (aa351-400)

AMM05905G 0.05ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human GHRHR (aa351-400). This antibody is tested and proven to work in the following applications:

Polyclonal PLEKHA8 Antibody (aa122-400)

AMM07243G 0.05ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PLEKHA8 (aa122-400). This antibody is tested and proven to work in the following applications:

Polyclonal TFG Antibody (aa350-400)

APR02435G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human TFG (aa350-400). This antibody is tested and proven to work in the following applications:

Polyclonal ALDH3A2 Antibody (aa166-400)

APG01760G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ALDH3A2 (aa166-400). This antibody is tested and proven to work in the following applications:

Anti-OXER1 (aa389-400) antibody

STJ72566 100 µg
EUR 430.8

Trypsin/Chrmotrypsin Complex 2400:400

T6789 5g
EUR 106.98

Biochrom EZ Read 400 ELISA

MIC8400 EACH
EUR 4775.46

Biochrom EZ Read 400 Research

MIC8402 EACH
EUR 5200.68

Stomacher 400 ECO Bag (Path.)

MIX3006 PK500
EUR 41.04

Stomacher 400 ECO Bag (TVC)

MIX3008 PK500
EUR 38.76

Stomacher 400 ECO Bag Opener

MIX3014 EACH
EUR 42.18

Blender Bag 400 Strainer Curved

MIX3109 PK200
EUR 108.3

SEPHACRYL S-400 HR, 750ML

GE17-0609-01 EACH
EUR 718.2

Adapter for 400 mL bottle

E5910706006 PK2
EUR 150.48

Sephacryl S-400 HR 750mL

17060901 EACH
EUR 785.46

Sephacryl S-400 HR 150mL

17060910 EACH
EUR 193.8

Vacutainer Blood Tube 400-600ul

365968 PK200
EUR 85.5

Ficoll Pm 400 100 G

17030010 EACH
EUR 189.24

Ficoll Pm 400 500 G

17030050 EACH
EUR 758.1

Caps Rubber Liner 24-400

TUB2726 PK144
EUR 257.64

Select Blender Bag 400 Standard

SLS3102 PK500
EUR 119.7

Select Blender Bag 400 Curved

SLS3103 PK500
EUR 119.7

Select Blender Bag 400 Strainer

SLS3108 PK200
EUR 156.18

Fc-gamma RIIb Recombinant Protein

91-400 0.05 mg
EUR 556.8
Description: Fc gamma RIIB is a low affinity receptor that recognizes the Fc portion of IgG. The human CD32 group consists of Fc gamma RIIA, Fc gamma RIIB, and Fc gamma RIIC proteins that share 94-99% sequence identity in their extracellular domains but differ substantially in their transmembrane and cytoplasmic domains. Fc gamma RII protein is expressed on cells of both myeloid and lymphoid lineages as well as on cells of non-hematopoietic origin. Fc gamma RIIB has an intrinsic cytoplasmic immunoreceptor tyrosine-based inhibitory motif (ITIM) and delivers an inhibitory signal upon ligand binding. Ligation of Fc gamma RIIB on B cells down-regulates antibody production and in some circumstances may promote apoptosis. Co-ligation of Fc gamma RIIB on dendritic cells inhibits maturation and blocks cell activation. Fc gamma RIIB may also be a target for monoclonal antibody therapy for malignancies. Fc gamma RIIB plays an important negative-regulating role through modulating the signals from activation receptors.

TRAIL R2 Recombinant Protein

92-400 0.05 mg
EUR 588.3
Description: Mouse tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) is a member of the TNFR family which contains 1 death domain and 3 TNFR-Cys repeats. TNFRSF10B exhibits high structural and functional homology to TRAIL-R1 (DR-4). TNFRSF10B is highly expressed in heart, lung, lymphocytes, spleen and kidney. In addition, it is regulated by the tumor suppressor p53. TNFRSF10B is the receptor for the cytotoxic ligand TNFSF10/TRAIL. It promotes the activation of NF-kappa-B and is essential for ER stress-induced apoptosis. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases mediating apoptosis.

Cellufine GCL-2000HF

21-400 100 ml
EUR 362.4

Cellufine MAX S-h

20-400 100 ml
EUR 458.4

Jurkat Cell Extract (Uninduced)

1106-400
EUR 222

Jurkat Cell Extract (Induced)

1107-400
EUR 222

Glypican 3 / GPC3 Recombinant Protein

11-400 0.1 mg
EUR 682.8
Description: Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.

SARS-CoV-2 (COVID-19) 3C-like Proteinase Recombinant Protein

10-400 0.1 mg
EUR 651.3
Description: The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents.

BEAKER,400ML,PLASTIC,LOW FORM,PP,6/6

1000P-400 6/pk
EUR 60
Description: Reusable Plastics; Resuable Beakers

AMV Reverse Transcriptase

105-400 200 units
EUR 75.6

Dilution Buffer

1066-400
EUR 314.4

Cell Lysis Buffer

1067-400
EUR 352.8

pAAV-GFP Control Vector

AAV-400 10 µg
EUR 679.2
Description: Use this control vector to co-transfect along with AAV packaging vectors to produce a recombinant AAV control.

ICAM 1 Recombinant Protein

96-400 0.2 mg
EUR 714.3
Description: Inter-Cellular Adhesion Molecule 1 (ICAM-1) is also known as Cluster of Differentiation 54 (CD54), is a member of the immunoglobulin superfamily, and is a cell surface glycoprotein which is typically expressed in low concentrations on endothelial cells and cells of the immune system. The protein encoded by this gene is a type of intercellular adhesion molecule continuously present in low concentrations in the membranes of leukocytes and endothelial cells. Upon cytokine stimulation, the concentrations greatly increase. ICAM-1 can be induced by interleukin-1 (IL-1) and tumor necrosis factor alpha (TNFα) and is expressed by the vascular endothelium, macrophages, and lymphocytes. ICAM-1 is a ligand for LFA-1 (integrin), a receptor found on leukocytes. When activated, leukocytes bind to endothelial cells via ICAM-1/LFA-1 and then transmigrate into tissues. ICAM-1 has been implicated in subarachnoid hemorrhage (SAH). Levels of ICAM-1 are shown to be significantly elevated in patients with SAH over control subjects in many studies. ICAM-1 expressed by respiratory epithelial cells is also the binding site for rhinovirus, the causative agent of most common colds.

CD80 Recombinant Protein

90-400 100 ug
EUR 651.3
Description: CD80 (B7-1) and CD86 (B7-2) together with their receptors CD28 and CTLA-4 constitute one of the dominant costimulatory pathways that regulate T cell and B cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells and macrophages. B7-2 is constitutively expressed on interdigitating dendritic cells, Langerhans cells, peripheral blood dendritic cells, memory B cells, and germinal center B cells. Additionally, B7-2 is expressed at low levels on monocytes and can be up-regulated through interferon-gamma. B7-1 and B7-2 are both members of the immunoglobulin superfamily. It has been observed that both human and mouse B7-1 and B7-2 can bind to either human or mouse CD28 and CTLA-4, suggesting that there are conserved amino acids which form the B7-1/B7-2/CD28/CTLA-4 critical binding sites.

Factor X, Human Plasma

7688-400
EUR 444

Factor Xa, Human Plasma

7689-400
EUR 489.6

SEALING FILM, FOR 96 AND 384 WELL MICROPLATES, RAYON, 50 µM, BREATHABLE, NONSTERILE, BULK

BF-400 100/pk
EUR 607.2
Description: Sealing Products; Sealing films - Axygen

Blood Advance? DNA Polymerase

M1153-400
EUR 568.8

amfiXpand Hot-Start Version , Including dNTP&MgCl2

P0334-400 20x200 units
EUR 2895.6

EZScreen? Alanine Aminotransferase (ALT or SGPT) Activity Assay Kit (384-Well)

K941-400
EUR 679.2

EZScreen? Triglyceride Quantification Colorimetric Assay Kit (384-well)

K952-400
EUR 751.2

EZScreen? Lactate Dehydrogenase Activity Colorimetric Assay Kit (384-well)

K953-400
EUR 666

EZScreen? Beta-Lactamase Activity Colorimetric Assay Kit (384-well)

K954-400
EUR 874.8

EZScreen? Free Fatty Acid Colorimetric Assay Kit (384-well)

K956-400
EUR 777.6

EZScreen? Total Cholesterol & Cholesteryl Ester Colorimetric Assay Kit (384-Well)

K957-400
EUR 718.8

EZScreen? NAD+/NADH Colorimetric Assay Kit (384-well)

K958-400
EUR 777.6

EZScreen? ATP Colorimetric Assay Kit (384-well)

K959-400
EUR 711.6

EZScreen? Glycogen Colorimetric Assay Kit (384-Well)

K960-400
EUR 777.6

Puredown Protein A-Agarose, BSA Blocked

P9201-400 40ml
EUR 1809.6

Puredown Protein G-Agarose, BSA Blocked

P9202-400 40ml
EUR 2522.4

Puredown Protein A/G-Agarose, BSA Blocked

P9203-400 40ml
EUR 2522.4

Serological Pipettes, 2ml , Sterile, Individually Wrapped

LC3062-400 400/pk
EUR 165.6

pLenti-GFP Lentiviral Control Vector

LTV-400 100 µL
EUR 741.6
Description: Use this control vector to co-transfect along with lentivirus packaging vectors to make a recombinant control lentivirus.

EnzyChrom Kinase Assay Kit

EKIN-400 400
EUR 356.4
Description: Rapid mix-and-measure procedure for determination of kinase activity and high-throµghput screening for kinase inhibitors by fluorimetric (530nm/590nm) method. Procedure: 10 min. Kit size: 400 tests. Detection limit: 0.01 U/L. Shelf life: 6 months. Shippin

LDH-Cytotoxicity Colorimetric Assay Kit

K311-400
EUR 464.4

Caspase-5 Fluorometric Assay Kit

K2195-400 400 assays
EUR 1336.8