micchem

Inhibitor of DNA binding 2 (Id2) mediates microtubule polymerization in the brain by regulating αK40 acetylation of α-tubulin

Acetylation of α-tubulin lysine 40 (αK40) contributes to microtubule (MT) stability and is crucial for neuronal improvement and performance, whereas extreme αK40 deacetylation is noticed in neurodegenerative problems together with Alzheimer’s illness (AD). Right here we recognized inhibitor of DNA binding 2 (Id2) as a novel MT-binding associate that interacts with α-tubulin and enhances αK40 acetylation, resulting in MT polymerization within the neurons. Commensurate with our discovering that the low ranges of Id2 expression together with a decreased αK40 acetylation within the postmortem human AD affected person and 5X-FAD, AD mannequin mice mind, Id2 upregulation within the hippocampus of 5X-FAD, which exhibit excessive ranges of Sirt2 expression, elevated αK40 acetylation and reconstitutes axon progress. Therefore our research means that Id2 is essential for sustaining MT stability throughout neural improvement and the potential of Id2 to counteract pathogenic Sirt2 exercise in AD.

Block copolymers primarily based on ethylene and methacrylates utilizing a mixture of catalytic chain switch polymerisation (CCTP) and radical polymerization

Two scalable polymerization strategies are utilized in mixture for the synthesis of ethylene and methacrylate block copolymers. ω-Unsaturated methacrylic oligomers (MMA n ) produced by catalytic chain switch (co)polymerisation (CCTP) of methyl methacrylate (MMA) and methacrylic acid (MAA) are used as reagents within the radical polymerization of ethylene (E) in dimethyl carbonate solvent beneath comparatively gentle situations (80 bar, 70°C). Kinetic measurements and analyses of the produced copolymers by dimension exclusion chromatography (SEC) and a mixture of nuclear magnetic resonance (NMR) strategies point out that MMA n is concerned in a degradative chain switch course of ensuing within the formation of (MMA) n – b -PE block copolymers. Molecular modelling carried out by DFT helps the general reactivity scheme and noticed selectivities. The impact of MMA n molar mass and composition can also be studied. The block copolymers have been characterised by differential scanning calorimetry (DSC) and their bulk behaviour studied by SAXS/WAXS evaluation.

Fabrication of hydrophilic zwitterionic microspheres by way of inverse suspension polymerization for the enrichment of N-glycopeptides

A form of zwitterionic microsphere was ready by way of one-step inverse suspension polymerization using 3-[N,N-dimethyl-[2-(2-methylpropyl-2-enyloxy) ethyl] ammonium] propane-1-sulfonate (MSA) and N,N-methylene bisacrylamide (BIS) because the precursors. The preparation situations have been fastidiously investigated and optimized by regulating the content material of complete monomers, ratio of MSA to BIS, ratio of water to grease, and content material of stabilizer.
The properties of microspheres have been characterised by helium ion microscopy (HIM), Fourier remodel infrared spectroscopy (FT-IR), X-ray photoelectron spectroscopy (XPS), N2 adsorption/desorption measurement, and water contact angle measurement.
The particle dimension of ensuing polydisperse microspheres ranged from 15-25 μm, exhibiting excessive particular floor space of 138 m2 g-1. Owing to nice hydrophilicity, the ensuing zwitterionic microspheres may very well be straight used as hydrophilic interplay chromatography (HILIC) sorbent to complement glycopeptides from biosamples with none chemical modification. A complete of 19 N-glycopeptides was enriched from 10 μg of IgG digest.
In addition to, as much as 383 N-glycopeptides and 224 N-glycosylation websites have been unambiguously recognized from 2 μL of human serum digest by cLC-MS/MS after enrichment with zwitterionic microspheres, indicating their nice enrichment efficiency to N-glycopeptides. The method of getting ready hydrophilic zwitterionic microspheres incorporates just one synthesis response and is appropriate for large-scale preparation.

Mussel-inspired adhesive antioxidant antibacterial hemostatic composite hydrogel wound dressing by way of photo-polymerization for contaminated pores and skin wound therapeutic

With the growing prevalence of drug-resistant bacterial infections and the gradual therapeutic of chronically contaminated wounds, the event of latest antibacterial and accelerated wound therapeutic dressings has develop into a severe problem. With a purpose to remedy this drawback, we developed photo-crosslinked multifunctional antibacterial adhesive anti-oxidant hemostatic hydrogel dressings primarily based on polyethylene glycol monomethyl ether modified glycidyl methacrylate functionalized chitosan (CSG-PEG), methacrylamide dopamine (DMA) and zinc ion for disinfection of drug-resistant micro organism and selling wound therapeutic. The mechanical properties, rheological properties and morphology of hydrogels have been characterised, and the biocompatibility of those hydrogels was studied via cell compatibility and blood compatibility exams.
These hydrogels have been examined for the in vitro blood-clotting potential of entire blood and confirmed good hemostatic potential within the mouse liver hemorrhage mannequin and the mouse-tail amputation mannequin. As well as, it has been confirmed that the multifunctional hydrogels have good inherent antibacterial properties in opposition to Methicillin-resistant Staphylococcus aureus (MRSA). Within the full-thickness pores and skin defect mannequin contaminated with MRSA, the wound closure ratio, thickness of granulation tissue, variety of collagen deposition, regeneration of blood vessels and hair follicles have been measured.
The inflammation-related cytokines (CD68) and angiogenesis-related cytokines (CD31) expressed throughout pores and skin regeneration have been studied. All outcomes point out that these multifunctional antibacterial adhesive hemostatic hydrogels have higher therapeutic results than commercially out there Tegaderm™ Movie, revealing that they’ve develop into promising different within the therapeutic of contaminated wounds.

Revealing Polymerization Kinetics with Colloidal Dipatch Particles

Restricted-valency colloidal particles can self-assemble into polymeric buildings analogous to molecules. Whereas their structural equilibrium properties have attracted extensive consideration, perception into their dynamics has confirmed difficult. Right here, we examine the polymerization dynamics of semiflexible polymers in 2D by direct statement of assembling divalent particles, bonded by essential Casimir forces.
The reversible essential Casimir power creates dwelling polymerization situations with tunable chain dissociation, affiliation, and bending rigidity. We discover that in contrast to dilute polymers that present exponential dimension distributions in wonderful settlement with Flory concept, concentrated samples exhibit arrest of rotational and translational diffusion because of a steady isotropic-to-nematic transition in 2D, slowing down the expansion kinetics.
These results are circumvented by the addition of higher-valency particles, cross linking the polymers into networks. Our outcomes connecting polymer flexibility, polymer interactions, and the peculiar isotropic-nematic transition in 2D provide perception into the polymerization processes of artificial two-dimensional polymers and biopolymers at membranes and interfaces.
micchem
micchem

Controllable Frontal Polymerization and Spontaneous Patterning Enabled by Part-Altering Particles

Frontal polymerization supplies a fast, financial, and environmentally pleasant methodology to fabricate thermoset polymers and composites. Regardless of its effectivity and decreased environmental affect, the manufacturing methodology is underutilized as a result of restricted elementary understanding of its dynamic management. This work experiences the management and patterning of the entrance propagation in a dicyclopentadiene resin by immersion of phase-changing polycaprolactone particles.
Predictive and designed patterning is enabled by multiphysical numerical analyses, which reveal that the interaction between endothermic part transition, exothermic chemical response, and warmth change govern the temperature, velocity, and propagation path of the entrance by way of two completely different interplay regimes. To sample the entrance, one can range the dimensions and spacing between the particles and enhance the variety of propagating fronts, leading to tunable bodily patterns shaped because of entrance separation and merging close to the particles. Each single- and double-frontal polymerization experiments in an open mildew are carried out.
The outcomes affirm the front-particle interplay mechanisms and the shapes of the patterns explored numerically. The current research provides a elementary understanding of frontal polymerization within the presence of heat-absorbing second-phase supplies and proposes a possible one-step manufacturing methodology for exactly patterned polymeric and composite supplies with out masks, molds, or printers.

OH-PEG-OH,400

HO002002-400-10g 10g
EUR 306
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

SH-PEG-SH,400

33-HO003003-400
  • EUR 259.00
  • EUR 677.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

COOH-PEG-COOH,400

33-HO017017-400
  • EUR 167.00
  • EUR 399.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

SC-PEG-SC,400

33-HO023023-400
  • EUR 167.00
  • EUR 399.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

HO-PEG-COOH,400

33-HE002017-400
  • EUR 198.00
  • EUR 494.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

SH-PEG-COOH,400

33-HE003017-400
  • EUR 519.00
  • EUR 1456.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

HS-PEG-NHS,400

33-HE003023-400
  • EUR 445.00
  • EUR 1234.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

SH-PEG-Biotin,400

33-HE003041-400
  • EUR 617.00
  • EUR 1751.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

NH2-PEG-COOH,400

33-HE005017-400
  • EUR 359.00
  • EUR 975.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

TruStrip Sample Transfer Strips, 400-ul, 50/Pk (without sample tracking dye)

STS-400-50 1 Pk Ask for price

TruStrip Sample Transfer Strips, 400-ul, 50/Pk (with sample tracking dye)

STSD-400-50 1 Pk Ask for price

SH-PEG-NH-Methoxyphenone,400

33-HE003071-400
  • EUR 519.00
  • EUR 1382.00
  • 100mg
  • 500mg
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

Ficoll 400

F760014 25g
EUR 90.02

Polysucrose 400

GC7257-100G 100 g
EUR 229

Polysucrose 400

GC7257-250G 250 g
EUR 429

Polysucrose 400

GC7257-25G 25 g
EUR 102

Polysucrose 400

abx082061-10g 10 g
EUR 189

Ficoll 400

abx082174-50g 50 g
EUR 272

Human Chorionic Gonadotropin (HCG) ELISA Kit, 96 tests, Quantitative

400 1 kit
EUR 469

Polyethylene glycol 400

GC3481-100G 100 g
EUR 41

Polyethylene glycol 400

GC3481-1KG 1 kg
EUR 65

Polyethylene glycol 400

GC3481-250G 250 g
EUR 46

Polyethylene glycol 400

GC3481-500G 500 g
EUR 53

Polyethylene glycol 400

GC3481-5KG 5 kg
EUR 153

mPEG-CH3?400

33-MF001049-400
  • EUR 233.00
  • EUR 599.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

Anti-Hex (400)

YF-MA13442 100 ug
EUR 363
Description: Mouse monoclonal to Hex

MAP3K8 (Ab-400) Antibody

CSB-PA901361-
EUR 335
Description: A polyclonal antibody against MAP3K8 (Ab-400). Recognizes MAP3K8 (Ab-400) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:3000, IHC:1:50-1:100

MAP3K8 (Ab-400) Antibody

CSB-PA901361-100ul 100ul
EUR 316
Description: A polyclonal antibody against MAP3K8 (Ab-400). Recognizes MAP3K8 (Ab-400) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:3000, IHC:1:50-1:100

MAP3K8 (Ab-400) Antibody

33235-100ul 100ul
EUR 252

MAP3K8 (Ab-400) Antibody

33235-50ul 50ul
EUR 187

Tau (pS717 / 400) Antibody

abx218901-100ug 100 ug
EUR 439

Alu I unit: 400

YRALU1 1 vial Ask for price

Bcl I unit: 400

YRBCL1 1 vial Ask for price

Bsp1286 I unit: 400

YRBSP1286 1 vial Ask for price

Nco I unit: 400

YRNCO1 1 vial Ask for price

Not I unit: 400

YRNOT1 1 vial Ask for price

Ssp I unit: 400

YRSSP1 1 vial Ask for price

MAPT (Ab-717/400) Antibody

CSB-PA112612-
EUR 335
Description: A polyclonal antibody against MAPT (Ab-717/400). Recognizes MAPT (Ab-717/400) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

MAPT (Ab-717/400) Antibody

CSB-PA112612-100ul 100ul
EUR 316
Description: A polyclonal antibody against MAPT (Ab-717/400). Recognizes MAPT (Ab-717/400) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

DiagNano Silica Particles, 400 nm

DNG-B008 10 mL
EUR 559

Trypsin/Chrmotrypsin Complex 2400:400

T6789 5g
EUR 89.15

Polyclonal PLEKHA8 Antibody (aa122-400)

AMM07243G 0.05ml
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PLEKHA8 (aa122-400). This antibody is tested and proven to work in the following applications:

Polyclonal SNX2 Antibody (aa350-400)

AMM07912G 0.05mg
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human SNX2 (aa350-400). This antibody is tested and proven to work in the following applications:

Polyclonal GHRHR Antibody (aa351-400)

AMM05905G 0.05ml
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human GHRHR (aa351-400). This antibody is tested and proven to work in the following applications:

Polyclonal NPY2R Antibody (aa350-400)

APR08798G 0.05mg
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human NPY2R (aa350-400). This antibody is tested and proven to work in the following applications:

Polyclonal ALDH3A2 Antibody (aa166-400)

APG01760G 0.05mg
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ALDH3A2 (aa166-400). This antibody is tested and proven to work in the following applications:

Polyclonal TFG Antibody (aa350-400)

APR02435G 0.05mg
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human TFG (aa350-400). This antibody is tested and proven to work in the following applications:

Tau (Phospho-Ser717/400) Antibody

12486-100ul 100ul
EUR 252

Tau (Phospho-Ser717/400) Antibody

12486-50ul 50ul
EUR 187

Tau (Ab-717/400) Antibody

33223-100ul 100ul
EUR 252

Tau (Ab-717/400) Antibody

33223-50ul 50ul
EUR 187

9998 SCREW CAP 400/24

9998-24 12/pk
EUR 54
Description: General Apparatus; Stoppers

9999 CAP ONLY 400/24

9999-24 12/pk
EUR 50
Description: General Apparatus; Stoppers

100 G POLYSUCROSE 400, POWDER

61-196-RM 100 g/pk
EUR 256
Description: Specialty Media; Insect Media Products

500 G POLYSUCROSE 400, POWDER

61-196-RO 500 g/pk
EUR 507
Description: Specialty Media; Insect Media Products

Anti-OXER1 (aa389-400) antibody

STJ72566 100 µg
EUR 359

MAP3K8 (Ab-400) Conjugated Antibody

C33235 100ul
EUR 397

Bromoacetyl resin (200-400 mesh)

D-2555.0001 1.0g
EUR 139

Bromoacetyl resin (200-400 mesh)

D-2555.0005 5.0g
EUR 441

Phospho-Tau (Ser717/400) Antibody

AF8129 200ul
EUR 376
Description: Tau (Phospho-Ser717/400) Antibody detects endogenous levels of Tau only when phosphorylated at Ser717/400.

Tau (Phospho- Ser717/400) Antibody

ABF8129 100 ug
EUR 438

Methoxy PEG Maleimide linear (MW: 10,000)

PEG-10K 100 mg
EUR 225

Methoxy PEG Maleimide lbranched (MW: 40,000)

PEG-40K 100 mg
EUR 225

Methoxy PEG Maleimide linear (MW: 5,000)

PEG-5K 100 mg
EUR 225

Serological Pipettes, 5ml, 400 per case

SP102116 1CS, 400UNIT
EUR 179.94

Serological Pipettes, 10ml, 400 per case

SP102121 1CS, 400UNIT
EUR 157.61

Polyclonal AGER / RAGE Antibody (aa350-400)

AMM05591G 0.05mg
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human AGER / RAGE (aa350-400). This antibody is tested and proven to work in the following applications:

Polyclonal PH / PAH Antibody (aa351-400)

APR09103G 0.05ml
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PH / PAH (aa351-400). This antibody is tested and proven to work in the following applications:

Polyclonal RNF216 / TRIAD3 Antibody (aa350-400)

APR02481G 0.05mg
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human RNF216 / TRIAD3 (aa350-400). This antibody is tested and proven to work in the following applications:

Polyclonal MAPK3 / ERK1 Antibody (aa350-400)

APR02823G 0.05mg
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human MAPK3 / ERK1 (aa350-400). This antibody is tested and proven to work in the following applications:

Polyclonal PPP1R10 / PNUTS Antibody (aa350-400)

APR12938G 0.05ml
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PPP1R10 / PNUTS (aa350-400). This antibody is tested and proven to work in the following applications:

Polyclonal HSPD1 / HSP60 Antibody (aa350-400)

APR16775G 0.05mg
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human HSPD1 / HSP60 (aa350-400). This antibody is tested and proven to work in the following applications:

Phospho-Tau (Ser717/400) Blocking Peptide

AF8129-BP 1mg
EUR 195

CLOuD9 Inducer Reagent (0.5M) - 400 ul

CASCL9-200A-1 200 ul
EUR 370

pLenti-GFP Lentiviral Control Vector

LTV-400 100 µL
EUR 618
Description: Use this control vector to co-transfect along with lentivirus packaging vectors to make a recombinant control lentivirus.

PLATEMAX PEELABLE HEAT SEALING FILM FOR COMPOUND STORAGE. 100/500

HS-400 100/pk
EUR 304
Description: Sealing Products; Sealing films - Axygen

Pan-Ras Activation Assay

STA-400 20 assays
EUR 757
Description: Our Ras Activation Assays use visible agarose beads to selectively precipitate the active form of specific Ras protein of interest. The precipitated small GTPase is then detected by Western blot using a target-specific antibody included in the kit. Assays are available to detect specific isoforms H-Ras, K-Ras, and N-Ras, as well as a Pan-Ras assay that detects all three isoforms.

0.1-20UL CLEAR EPPENDORF ULTRA MICRO TIPS

T-400 1000/pk
EUR 220
Description: Non Filter Tips; Pipette Tips - Axygen

amfiXpand Hot-Start Version , Including dNTP&MgCl2

P0334-400 20x200 units
EUR 2413

Puredown Protein A-Agarose, BSA Blocked

P9201-400 40ml
EUR 1508

Puredown Protein G-Agarose, BSA Blocked

P9202-400 40ml
EUR 2102

Puredown Protein A/G-Agarose, BSA Blocked

P9203-400 40ml
EUR 2102

Serological Pipettes, 2ml , Sterile, Individually Wrapped

LC3062-400 400/pk
EUR 138

1Kb PCR Ranger DNA Marker, 750bp-To-20Kb

D1109-400 4x1ml
EUR 388

0.1-10UL FILTER TIPS FOR EPPENDORF ULTRAMICRO

TF-400 1000/pk
EUR 418
Description: Filter Tip; Filter Tips Pipette - Axygen

Cellufine MAX S-h

20-400 100 ml
EUR 382

Cellufine GCL-2000HF

21-400 100 ml
EUR 302

BEAKER,400ML,PLASTIC,LOW FORM,PP,6/6

1000P-400 6/pk
EUR 50
Description: Reusable Plastics; Resuable Beakers

AMV Reverse Transcriptase

105-400 200 units
EUR 63

pAAV-GFP Control Vector

AAV-400 10 µg
EUR 566
Description: Use this control vector to co-transfect along with AAV packaging vectors to produce a recombinant AAV control.

SEALING FILM, FOR 96 AND 384 WELL MICROPLATES, RAYON, 50 µM, BREATHABLE, NONSTERILE, BULK

BF-400 100/pk
EUR 506
Description: Sealing Products; Sealing films - Axygen

Trypin for Mass & Sequencing

T9600-400 4x100ug
EUR 651

Zenoprep Genomic DNA Purification Kit

Z2004-400 400 preps
EUR 550

Recombinant (E.Coli) Human Set7/9 histone Methyltransferase

RP-400 20 ug
EUR 164

Annexin V-FITC Apoptosis Kit

K2003-400 400 assays
EUR 1114

Annexin V-Cy3 Apoptosis Kit

K2004-400 400 assays
EUR 1114

Annexin V-Cy5 Apoptosis Kit

K2005-400 400 assays
EUR 1114

Annexin V-EGFP Apoptosis Kit

K2006-400 400 assays
EUR 1114

Caspase-3 Fluorometric Assay Kit

K2007-400 400 assays
EUR 1086

Caspase-3 Colorimetric Assay Kit

K2008-400 400 assays
EUR 1086

Annexin V-Biotin Apoptosis Kit

K2009-400 400 assays
EUR 1114

Caspase-1 Fluorometric Assay Kit

K2010-400 400 assays
EUR 1086

Caspase-1 Colorimetric Assay Kit

K2011-400 400 assays
EUR 1086

Caspase-8 Fluorometric Assay Kit

K2012-400 400 assays
EUR 1086

Caspase-8 Colorimetric Assay Kit

K2013-400 400 assays
EUR 1086

Caspase-6 Fluorometric Assay Kit

K2014-400 400 assays
EUR 1086

Caspase-6 Colorimetric Assay Kit

K2015-400 400 assays
EUR 1101

Caspase-2 Fluorometric Assay Kit

K2016-400 400 assays
EUR 1114

Caspase-2 Colorimetric Assay Kit

K2017-400 400 assays
EUR 1156

Caspase-9 Fluorometric Assay Kit

K2018-400 400 assays
EUR 1114

Caspase-9 Colorimetric Assay Kit

K2019-400 400 assays
EUR 1156

LDH-Cytotoxicity Colorimetric Assay Kit

K2025-400 400 assays
EUR 390

Annexin V-FITC Apoptosis Kit Plus

K2057-400 400 assays
EUR 1059

Annexin V-Cy3 Apoptosis Kit Plus

K2058-400 400 assays
EUR 1059

Annexin V-PE Apoptosis Kit Plus

K2059-400 400 assays
EUR 1059

Caspase-5 Fluorometric Assay Kit

K2195-400 400 assays
EUR 1114

Caspase-5 Colorimetric Assay Kit

K2196-400 400 assays
EUR 1156

Caspase-10 Colorimetric Assay Kit

K2197-400 400 assays
EUR 1114

Caspase-4 Fluorometric Assay Kit

K2198-400 400 assays
EUR 1114

Caspase-4 Colorimetric Assay Kit

K2199-400 400 assays
EUR 1114

Annexin V-PE Apoptosis Detection Kit

K2200-400 400 assays
EUR 1114

Annexin V-PE-Cy5 Apoptosis Detection Kit

K2201-400 400 assays
EUR 1253

EnzyChrom Kinase Assay Kit

EKIN-400 400
EUR 297
Description: Rapid mix-and-measure procedure for determination of kinase activity and high-throµghput screening for kinase inhibitors by fluorimetric (530nm/590nm) method. Procedure: 10 min. Kit size: 400 tests. Detection limit: 0.01 U/L. Shelf life: 6 months. Shippin

dATP, dCTP, dGTP, dTTP

K6011100-400 4x400 ul (100 mM)
EUR 235
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

dATP

K6011101-400 400 ul (100 mM)
EUR 116
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

dGTP

K6011102-400 400 ul (100 mM)
EUR 116
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

dCTP

K6011103-400 400 ul (100 mM)
EUR 116
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

dTTP

K6011104-400 400 ul (100 mM)
EUR 116
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

dNTP Mix

K6011105-400 400 ul (10 mM each)
EUR 116
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

SARS-CoV-2 (COVID-19) 3C-like Proteinase Recombinant Protein

10-400 0.1 mg
EUR 542.75
Description: The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents.

Glypican 3 / GPC3 Recombinant Protein

11-400 0.1 mg
EUR 569
Description: Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.

ICAM 1 Recombinant Protein

96-400 0.2 mg
EUR 595.25
Description: Inter-Cellular Adhesion Molecule 1 (ICAM-1) is also known as Cluster of Differentiation 54 (CD54), is a member of the immunoglobulin superfamily, and is a cell surface glycoprotein which is typically expressed in low concentrations on endothelial cells and cells of the immune system. The protein encoded by this gene is a type of intercellular adhesion molecule continuously present in low concentrations in the membranes of leukocytes and endothelial cells. Upon cytokine stimulation, the concentrations greatly increase. ICAM-1 can be induced by interleukin-1 (IL-1) and tumor necrosis factor alpha (TNFα) and is expressed by the vascular endothelium, macrophages, and lymphocytes. ICAM-1 is a ligand for LFA-1 (integrin), a receptor found on leukocytes. When activated, leukocytes bind to endothelial cells via ICAM-1/LFA-1 and then transmigrate into tissues. ICAM-1 has been implicated in subarachnoid hemorrhage (SAH). Levels of ICAM-1 are shown to be significantly elevated in patients with SAH over control subjects in many studies. ICAM-1 expressed by respiratory epithelial cells is also the binding site for rhinovirus, the causative agent of most common colds.

Annexin V-FITC Apoptosis Kit

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Annexin V-Cy3 Apoptosis Kit

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Annexin V-Cy5 Apoptosis Kit

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Annexin V-EGFP Apoptosis Kit

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Caspase-3 Fluorometric Assay Kit

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Caspase-3 Colorimetric Assay Kit

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Annexin V-Biotin Apoptosis Kit

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Caspase-1 Fluorometric Assay Kit

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Caspase-1 Colorimetric Assay Kit

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Caspase-8 Fluorometric Assay Kit

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Caspase-8 Colorimetric Assay Kit

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Caspase-6 Fluorometric Assay Kit

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Caspase-6 Colorimetric Assay Kit

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Caspase-2 Fluorometric Assay Kit

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Caspase-2 Colorimetric Assay Kit

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Caspase-9 Fluorometric Assay Kit

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Caspase-9 Colorimetric Assay Kit

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Caspase-5 Fluorometric Assay Kit

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Caspase-5 Colorimetric Assay Kit

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Caspase-10 Fluorometric Assay Kit

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Caspase-10 Colorimetric Assay Kit

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Caspase-4 Fluorometric Assay Kit

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Caspase-4 Colorimetric Assay Kit

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Annexin V-PE Apoptosis Detection Kit

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Annexin V-PE-Cy5 Apoptosis Detection Kit

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Annexin V-FITC Apoptosis Kit Plus

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Annexin V-Cy3 Apoptosis Kit Plus

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Annexin V-PE Apoptosis Kit Plus

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LDH-Cytotoxicity Colorimetric Assay Kit

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EZScreen? Alanine Aminotransferase (ALT or SGPT) Activity Assay Kit (384-Well)

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EZScreen? Triglyceride Quantification Colorimetric Assay Kit (384-well)

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EZScreen? Lactate Dehydrogenase Activity Colorimetric Assay Kit (384-well)

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