micchem

Influence of polyethylene terephthalate/ polyamide (PET/PA) bilayer structure on physical and strength-related properties of superpressure angioplasty balloons

  Background: Percutaneous transluminal coronary angioplasty (PTCA), together with balloon angioplasty, is a regular scientific invasive therapy for coronary artery illness. The coronary lesion with calcification is tough to dilate and the prevention of balloon failure is particularly vital.   Goal: A novel superpressure balloon was fabricated with bilayered construction of polyethylene terephthalate (PET) and PA12 (polyamide).…

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Molecular Recognition of the HPLC Whelk-O1 Selector towards the Conformational Enantiomers of Nevirapine and Oxcarbazepine

Molecular Recognition of the HPLC Whelk-O1 Selector towards the Conformational Enantiomers of Nevirapine and Oxcarbazepine

The presence of stereogenic parts is a standard characteristic in pharmaceutical compounds, and affording optically pure stereoisomers is a frequent difficulty in drug design. On this context, the examine of the chiral molecular recognition mechanism essentially helps the understanding and optimization of chromatographic separations with chiral stationary phases. We investigated, with molecular docking, the interactions…

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Spinochrome Identification and Quantification in Pacific Sea Urchin Shells, Coelomic Fluid and Eggs Using HPLC-DAD-MS

Spinochrome Identification and Quantification in Pacific Sea Urchin Shells, Coelomic Fluid and Eggs Using HPLC-DAD-MS

The high-performance liquid chromatography technique coupled with diode array and mass spectrometric detector (HPLC-DAD-MS) technique for quinonoid pigment identification and quantification in sea urchin samples was developed and validated. The composition and quantitative ratio of the quinonoid pigments of the shells of 16 species of sea urchins, collected within the temperate (Sea of Japan) and…

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HPLC Determination of Imidazoles with Variant Anti-Infective Activity in Their Dosage Forms and Human Plasma

HPLC-DAD-MS and Antioxidant Profile of Fractions from Amontillado Sherry Wine Obtained Using High-Speed Counter-Current Chromatography

Within the current work, the polyphenolic profile of a posh matrix equivalent to Amontillado sherry has been processed via high-speed counter-current chromatography (HSCCC) and characterised by HPLC-DAD-MS. An Amberlite XAD-7 column was used to acquire the wine extract, and three totally different biphasic solvent methods had been utilized for HSCCC separation: MTBE (methyl tert-butyl ether)/n-butanol/acetonitrile/water (1.1/3/1.1/5+0.1%…

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