Category: Isotypes

Molecular Recognition of the HPLC Whelk-O1 Selector towards the Conformational Enantiomers of Nevirapine and Oxcarbazepine

The presence of stereogenic parts is a standard characteristic in pharmaceutical compounds, and affording optically pure stereoisomers is a frequent difficulty in drug design. On this context, the examine of the chiral molecular recognition mechanism essentially helps the understanding and optimization of chromatographic separations with chiral stationary phases. We investigated, with molecular docking, the interactions

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HPLC coupled with quadrupole time of flight tandem mass spectrometry for analysis of glycosylated components from the fresh flowers of two congeneric species: Robinia hispida L. and Robinia pseudoacacia L

Creating strategies for the systematic and speedy identification of the chemical compositions of contemporary plant tissues has lengthy attracted the eye of phytochemists and pharmacologists. Within the current research, primarily based on extremely environment friendly pattern pretreatment and high-throughput evaluation of HPLC coupled with quadrupole time of flight tandem mass spectrometry knowledge utilizing molecular networks,

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HPLC-DAD-MS and Antioxidant Profile of Fractions from Amontillado Sherry Wine Obtained Using High-Speed Counter-Current Chromatography

Within the current work, the polyphenolic profile of a posh matrix equivalent to Amontillado sherry has been processed via high-speed counter-current chromatography (HSCCC) and characterised by HPLC-DAD-MS. An Amberlite XAD-7 column was used to acquire the wine extract, and three totally different biphasic solvent methods had been utilized for HSCCC separation: MTBE (methyl tert-butyl ether)/n-butanol/acetonitrile/water (1.1/3/1.1/5+0.1%

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