Category: Elisa Kits

Molecular Recognition of the HPLC Whelk-O1 Selector towards the Conformational Enantiomers of Nevirapine and Oxcarbazepine

The presence of stereogenic parts is a standard characteristic in pharmaceutical compounds, and affording optically pure stereoisomers is a frequent difficulty in drug design. On this context, the examine of the chiral molecular recognition mechanism essentially helps the understanding and optimization of chromatographic separations with chiral stationary phases. We investigated, with molecular docking, the interactions

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HPLC Determination of Imidazoles with Variant Anti-Infective Activity in Their Dosage Forms and Human Plasma

An appropriate HPLC technique has been chosen and validated for speedy simultaneous separation and dedication of 4 imidazole anti-infective medication, secnidazole, omeprazole, albendazole, and fenbendazole, of their closing dosage types, along with human plasma inside 5 min. The tactic suitability was derived from the prevalence of utilizing the environmentally benign solvent, methanol over acetonitrile as

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Single-run reversed-phase HPLC method for determining sertraline content, enantiomeric purity, and related substances in drug substance and finished product

A direct enantio-, diastereo-, and chemo-selective high-performance liquid chromatographic methodology was developed for figuring out the content material, enantiomeric purity, and associated substances of the chiral antidepressant drug sertraline HCl in a single chromatographic run. The separation was achieved on a chiral stationary part based mostly on amylose tris(3-chloro-5-methylphenylcarbamate) beneath reversed-phase circumstances. The strategy was

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