Category: Clia Kits

Molecular Recognition of the HPLC Whelk-O1 Selector towards the Conformational Enantiomers of Nevirapine and Oxcarbazepine

The presence of stereogenic parts is a standard characteristic in pharmaceutical compounds, and affording optically pure stereoisomers is a frequent difficulty in drug design. On this context, the examine of the chiral molecular recognition mechanism essentially helps the understanding and optimization of chromatographic separations with chiral stationary phases. We investigated, with molecular docking, the interactions

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HPLC coupled with quadrupole time of flight tandem mass spectrometry for analysis of glycosylated components from the fresh flowers of two congeneric species: Robinia hispida L. and Robinia pseudoacacia L

Creating strategies for the systematic and speedy identification of the chemical compositions of contemporary plant tissues has lengthy attracted the eye of phytochemists and pharmacologists. Within the current research, primarily based on extremely environment friendly pattern pretreatment and high-throughput evaluation of HPLC coupled with quadrupole time of flight tandem mass spectrometry knowledge utilizing molecular networks,

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HPLC Determination of Imidazoles with Variant Anti-Infective Activity in Their Dosage Forms and Human Plasma

An appropriate HPLC technique has been chosen and validated for speedy simultaneous separation and dedication of 4 imidazole anti-infective medication, secnidazole, omeprazole, albendazole, and fenbendazole, of their closing dosage types, along with human plasma inside 5 min. The tactic suitability was derived from the prevalence of utilizing the environmentally benign solvent, methanol over acetonitrile as

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Single-run reversed-phase HPLC method for determining sertraline content, enantiomeric purity, and related substances in drug substance and finished product

A direct enantio-, diastereo-, and chemo-selective high-performance liquid chromatographic methodology was developed for figuring out the content material, enantiomeric purity, and associated substances of the chiral antidepressant drug sertraline HCl in a single chromatographic run. The separation was achieved on a chiral stationary part based mostly on amylose tris(3-chloro-5-methylphenylcarbamate) beneath reversed-phase circumstances. The strategy was

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HPLC-DAD-MS and Antioxidant Profile of Fractions from Amontillado Sherry Wine Obtained Using High-Speed Counter-Current Chromatography

Within the current work, the polyphenolic profile of a posh matrix equivalent to Amontillado sherry has been processed via high-speed counter-current chromatography (HSCCC) and characterised by HPLC-DAD-MS. An Amberlite XAD-7 column was used to acquire the wine extract, and three totally different biphasic solvent methods had been utilized for HSCCC separation: MTBE (methyl tert-butyl ether)/n-butanol/acetonitrile/water (1.1/3/1.1/5+0.1%

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