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Xylitol
XYLITOL, a pentapolyhydric alcohol, is one
of the normal metabolic intermediates in the important non-glycolysis
systems of human body. It exhibits a strong anti-ketogenic effect,
and metabolizes irrespective of insulin. For pharmaceutical use,
it is used in an infusion for patients with abnormal carbohydrate
metabolism or for insulin shock treatment because it has no influence
on either the glycogen synthesis or the blood sugar level of diabetes
mellitus.
The additional properties of XYLITOL are that
it is chemically stable and only slightly hygroscopic, is soluble
in water, and possesses a cool and refreshing taste as sweet as
sugar. Another eminent property of XYLITOL is that it does not promote
tooth decay so that it is used in toothpaste, sugarless confectioneries
such as chewing gum, candy and chocolate.
| Product
Specification |
| Xylitol
FCC 3 |
| Test
Items |
Specifications |
| Description |
White crystals
or crystalline powder.
It has a sweet taste and produces a cooling sensation
in the mouth. One gram dissolves in about 0.65ml of water.
It is sparingly soluble in alcohol.
Crystalline Xylitol has a melting range between 92°
C
and 96° C |
| Identification |
| A |
The crystals
melt between 195° C and 201° C |
| B |
The infrared absorption spectrum
of a potassium bromide dispersion of the sample exhibits
maxima only at
the same wavelength as that of a similar preparation of
FCC Xylitol Reference standard. |
| Assay |
98.5 -101.0 % |
| Arsenic |
Not more than 3 ppm |
| Heavy Metals |
Not more than 10 PPM |
| Loss on Drying |
Not more than 0.5 % |
| Other Polyols |
Not more than 2.0 % |
| Reducing Sugars |
Not more than 0.2 % |
|
| Xylitol
JP XII |
| Test
Items |
Specifications |
| Description |
White crystals or crystalline
powder. It is odorless, and has a sweet taste. It is very
soluble in water, and practically insoluble in ethanol
and in ether. It is hygroscopic. |
| Identification |
|
| (1) |
The crystals melt between
195°C and 201°C. |
| (2) |
A blue-green color develops,
but no turbidity is produced. |
| (3) |
The crystals melt between
61°C and 64°C. |
| pH |
5.0-7.0 |
| Melting Point |
93.0-95.O°C |
| Purity |
|
| (1) Clarity and Color of
Solution |
The solution is clear and
colorless. |
(2) Chloride
|
Not more than 0.005 % |
| (3) Sulfate |
Not more than 0.006 % |
| (4) Heavy Metals |
Not more than 5 PPM |
| (5) Nickel |
No red color is produced. |
| (6) Arsenic |
Not more than 1.3 PPM |
| (7) Sugars |
Not more than 1.0ml of 0.1N
KMnO4 |
| Loss on Drying |
Not more than 1.0% |
| Residue on Ignition |
Not more than 0.10% |
| Assay |
Not less than 98.0% |
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